Lý lịch khoa học
Nguyễn Thị Mai Thu

Chức vụ: Nhân viên cấp cao nghiên cứu, Khoa Y, Trung tâm Bệnh Truyền nhiễm, Trung Tâm Y Khoa Đại học Duke

Chuyên ngành: Di truyền sinh học.

Email: thu.t.nguyen@duke.edu

GIỚI THIỆU BẢN THÂN

Học vấn

Thời gian

Nơi công tác

Công tác

2002–2006

CN Sinh học, Đại học Khoa Học Tự nhiên Đại học Quốc Gia TP.HCM, TP.HCM, Vietnam

Chuyên ngành Di truyền sinh học

2013-2017

ThS Vi sinh học, Đại học Khoa Học Tự nhiên Đại học Quốc Gia TP.HCM, TP.HCM, Vietnam

Luận văn: “Clinical performance of the Mp1p Immunoassay for Rapid Diagnosis of              Talaromyces marneffei infection”

Kinh nghiệm nghiên cứu

Thời gian

Nơi công tác

Công việc đảm nhiệm

2008 – 2012

Viện Pasteur TP.HCM, Vietnam

Trợ lý nghiên cứu

2012 – 2018

Viên nghiên cứu lâm sàng Oxford (OUCRU)

Trợ lý nghiên cứu cấp cao

2018 – nay

Khoa Y, Trung tâm Bệnh Truyền nhiễm, Trung Tâm Y Khoa Đại học Duke

Nhân viên cấp cao nghiên cứu
Quá trình

NGHIÊN CỨU KHOA HỌC

  1. Thu NTM, Dieu NQ, Hao NT, Ly VT, Thach PN, Trinh PL, Khanh DH, Men TT, Dao PTH, Thom VT, Chau TTH, Jasper FW Chan, Yuen KY, Dat VQ, Rogier VD, Thuy Le. Multi-center Prospective Validation Study of a Novel Mp1p Antigen Assay for Talaromycosis. Conference of Retroviruses and Opportunistic Infections. Feb 19-22, 2023. Seattle, WS, USA.
  2. Thu NTM,Hannah S, Shawin V, Navsin K, Kaushik SR, Josep B, Thuy Le. Development and Standardization of a Novel Colorimetric Antifungal Susceptibility Tesing method for the Dimorphic Fungus Talaromyces marneffei. The 18th Annula Duke Center for AIDS Research Fall Scientific Retreat.
  3. Thu NTM, Hannah S, Ly VT, Thanh NT, Thuy Le. In-Vitro Antifungal Susceptibility and Antifungal Treatment Outcome in talaromycosis. Conference of Retroviruses and Opportunistic Infections. Mar 08-11, 2020. Boston, MS, USA.
  4. Thu NTM, Ly VT, Thanh NT, Tung NLN, Jasper F. Chan, Patrik Woo, Chau NVV, Nga CN, Yuen KY, Thuy Le. Making an early diagnosis of talaromycosis using a novel antigen assay. Molecular Genetics and Microbiology retreat and Duke CFAR in 2019. Durham, US.
  5. Nguyen T. Thu, Vu Quoc Dat, Jasper F. Chan, Hien T. Ha, Dung T. Nguyen, Anh T. Ho, Patrick C. Woo, Kwok-Yung Yuen, Sheryl Lyss, Moses Bateganya, Kinh V. Nguyen, Thuy Le. Asymptomatic Talaromyces marneffei antigenemia and mortality in advanced HIV disease. Conference of Retroviruses and Opportunistic Infections. Mar 04-07, 2019. Seattle, WA, USA
  6. Thu N, Dat V, Chan J, Hien H, Anh D, Ha N, K’Voi L, Dung N, Anh H, Woo P, Yuen K, Lyss S, Kinh N, Bateganya M, Le T. Asymptomatic Talaromyces marneffeiinfection is associated with HIV mortality. Oral presentation at session of Co-infections and complications. 3rd Asia Pacific AIDS and Coinfection Conference, June 28-30, 2018. Hong Kong
  7. Thu NTM, Chan JFW, Hien HTA, Tung NLN, Thanh NT, Day JN, Vinh Chau NV, Thwaites G, Woo P, Yuen KY, Le T. Clinical Performance of the Mp1p Immunoassay for Rapid Diagnosis of Talaromyces marneffei Conference of Retroviruses and Opportunistic Infections. Feb 13-16, 2017. Seattle, WA, USA
  8. Thu NTM, Hien HTA, Tung NLN, Day J, Vinh Chau NV, Thwaites G, Chan FWC, Yuen KY, and Le T. Rapid serodiagnosis of Talaromyces marneffei 5th Vietnam National Conference in Infectious Diseases and HIV. Sep 17-18, 2016. Hanoi, Vietnam
  9. Thu NTM, Hien HTA, Nguyen A, Kim Cuc NT, Huong Lan NP, Thanh NT, Anh DV, Day JN, Thwaites G and Le T. A Simple Culturing Method for Detection and Quantification of Talaromyces marneffeiin Patient Blood. 1st Asia Pacific AIDS and Coinfection Conference, May 17-19, 2016. Hong Kong.
Công trình đã công bố

CÔNG BỐ QUỐC TẾ

  1. Sephton-Clark P, Nguyen T, Hoa NT, Ashton P, van Doorn HR, Ly VT, Le T, Cuomo CA. Impact of pathogen genetics on clinical phenotypes in a population of Talaromyces marneffei from Vietnam. Genetics. 2023 May 25;. doi: 10.1093/genetics/iyad100. [Epub ahead of print] PubMed PMID: 37226893.
  2. Stott KE, Le T, Nguyen T, Whalley S, Unsworth J, Ly VT, Kolamunnage-Dona R, Hope W. Population Pharmacokinetics and Pharmacodynamics of Itraconazole for Disseminated Infection Caused by Talaromyces marneffei. Antimicrob Agents Chemother. 2021 Oct 18;65(11):e0063621. doi: 10.1128/AAC.00636-21. Epub 2021 Aug 9. PMID: 34370587; PMCID: PMC8522747.
  3. Thu NTM, Chan JFW, Ly VT, et al. Superiority of a novel Mp1p antigen detection enzyme immunoassay compared to standard BACTEC blood culture in the diagnosis of talaromycosis. Clin Infect Dis2021
  4. Cuomo CA, Shea T, Nguyen T, Ashton P, PerfectJ, Le T. Complete Genome Sequences for Two Talaromyces marneffei Clinical Isolates from Northern and Southern Vietnam. Microbiol Resour Announc. 2020 Jan 9;9(2). doi: 10.1128/MRA.01367-19. PubMed PMID: 31919177; PubMed Central PMCID: PMC6952663.
  5. Ly VT, Thanh NT, Thu NTM, et al. Occult Talaromyces marneffei Infection Unveiled By the Novel Mp1p Antigen Detection Assay. Open Forum Infectious Diseases
  6. Le T, Ly VT, Thu NTM, Nguyen A, Thanh NT, Vinh Chau NV, Thwaites G, Perfect J, Kolamunnage-Dona R, Hope W. Population pharmacodynamics of Amphotericin B Deoxycholate for disseminated infection caused by Talaromyces marneffei. Antimicrob Agents Chemother. 2018 Nov 12. pii: AAC.01739-18. doi:10.1128/AAC.01739-18. PubMed PMID: 30420478.
  7. Hien HT, Thanh TT, Thu NT, Nguyen A, Thanh NT, Lan NP, Simmons C, Shikuma C, Chau NV, Thwaites G, Le T. Development and evaluation of a real-time polymerase chain reaction assay for the rapid detection of Talaromyces marneffeiMP1 gene in human plasma. Mycoses. 2016 Jul 25. doi: 10.1111/myc.12530. PubMed PMID: 27453379.
  8. Le T, Kinh NV, Cuc NTK, Tung NNL, Lam NT, Thuy PTT, Cuong DD, Phuc PTH, Vinh VH, Hanh DTH, Tam VV, Thanh NT, Thuy TP, Hang NT, Long HB, Nhan HT, Wertheim HFL, Merson L, Shikuma C, Day JN, Vinh Chau NV, Farrar J, Thwaites G and Wolbers, M for IVAP investigators. A Trial of Itraconazole or Amphotericin B for HIV-Associated Talaromycosis. N Engl J Med. 2017; 376:2329-40. doi: 10.1056/NEJMoa1613306.